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SYM 2081(CAT: R002858) is a high-affinity, potent, and selective agonist of kainate receptors, exhibiting an IC₅₀ of 35 nM for inhibition of [³H]-kainate binding. It demonstrates exceptional receptor selectivity, being approximately 3,000-fold more selective for
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SYM 2081 is a kainate receptor agonist. SYM 2081 is a substrate of EAAT1 (Km of 54 μM). SYM 2081 inhibits EAAT2-mediated glutamate transport (Kb is 3.4 μM in Xenopus oocytes), modulates Apoptotic signaling pathways
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90
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Merck KGaA
100 lm sym 2081 100 Lm Sym 2081, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/sym+2081/100+lm+sym+2081/pm16222546-38-67-83 Average 90 stars, based on 1 article reviews
100 lm sym 2081 - by Bioz Stars,
2026-10
90/100 stars
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SYM 2081 is a highly selective and potent kainate receptor agonist with IC50 for 35 nM, which is almost 200- and 3,000-fold selectivity over NMDA and AMPA receptors respectively. It also selectively inhibits the cloned
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